SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c8d1519247694f83a7fba5e39f11b7fafeb781371c85fb3ed3c31ab0cc75d8' 
  AND token = 'V9F8ianeDFJgTyJOb6e64kIk6zdx4IGGMBLFTeqDIvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}