SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a90ada2a6ab70476f2aa527280c841a3f2da53260fe1ae0dc7dd2d481f4adf45' 
  AND token = '2mKzT2ctLzuKvGToR3iSuitx33B0fXFkaAjttgSFWqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}