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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '651cef175d9ccfecb4cd5a4fed9cfe46b50747474c951be3da9e88fc684ef47c' 
  AND token = 'FRf7Ltd0KRBmKCKXtucYbDS9iXQwJXtWeRZYBEctSqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}