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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5cbac3a3575fbcf46300a344b3a12b4e50125bd5b813a510819f966078812cf' 
  AND token = 'PUOS/2OIjepa3UpRGOQXl9re7660bb/5hkPBmGez7R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}