SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77423cd88b13b6e69fffa03c1932b7729a4c52d81b094b61f92a0fab4c76a22e' 
  AND token = 'qfBWYCbRbRvFonJDYxTcMXgtZXyaBabMBXD0ieVaj9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}