SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25d22df72db2e2739f27d22d782a1ec34204131453847fa73ed994a5a262dc2' 
  AND token = 'j9i5EBgQOG2C3OPwgwIfpY55HLC6Itpp0zdzKUg/ZUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}