SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b714808a0ec2708b46d82c6ec481bfc6246d177d7eb74c51b031d4ec26d6f2' 
  AND token = 'pIlQ94/8qop3rUEE1EQ2eV3Sz81WGPLnXkcbjIp0N9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}