SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ae13349ad668b64a7c8c1e3a7d97e032c5df2f65396cf9fd3a77a31b7ce2e0' 
  AND token = 'xaVxcg4cUtdtLi49tQBZOzhy4Vb1F7r9DJLlYM6AKhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}