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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c541ab5988d15701641d76db762d04e8825966553238db33e60c5fc71c43fc' 
  AND token = '1edXrcvMgxQsdCX47/rXfcrwTUvxhP3G/3jPF8b0lPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}