SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39443b7d4a4d495e8fc739dba5f5ea06849f027d7555df2eb4f62d6b260b95c' 
  AND token = 'xEl1XTtc8k/Ut2/jKAMW6y//TW/19cgDdrrurNTq1Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}