SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a55b2910633b27400fd6f15a2d46b37337813f452d53873b5f985f90122fc3' 
  AND token = 'gjUOCMgLuuK/md309fWOgVD3ceQuNb62wrDUpyYAd4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}