SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f545b013969c4ce651326ccc11d6ed828e7ffb3cda39a6fb80b4809d78a000e8' 
  AND token = 'uUxCitYNgNg9ImDSs6aZcw7H2c1vBdLrWjoI+p1fhjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}