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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e918f62064588272e7fc4c54474b068a1215e279ea8bc006ef262db76f34a960' 
  AND token = 'U/CeJCmivPAvxOFXDMHTo+ghrebmDJb8g/azcFdrA4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}