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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33119fa76d870022c5984b3eb8b378bf9d3c8b14b9279ebbfc69fee53a3301d' 
  AND token = 'E/qD4mwfblaOXkiQCDRrpqw1W/Z9aaxcw0gQatKv1bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}