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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2821b391d53cd9c9375f853293d1c26538fe59e4dd1d1fab4bf9fb3c1827155f' 
  AND token = 'KSwMtRDytW3U54tH5A3m+xth9NZeLtQ88fjMkb2kAes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}