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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b458ab1159edd96568d08e45bba56d3746b1b0bafd2190a2521ba1cbecb1ec0e' 
  AND token = 'hRxCUuAQbpQKlU+yZtKuqZ7khE4YglDS0ZtMp6tvCQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}