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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37865b937ea5fccc270eeb34319cefdf8c38676c9fd7e2c033ce3e63e4dad54' 
  AND token = 'ARdlKo1OXndk+JFSJ63S02Tps6nTQ9RS9Xlo34XSTfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}