SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53df8d1c946144b1f0710e5f29c3685cbee9ae5374b50dc4a0101eac391b67c' 
  AND token = '8NRoPgXaKmuopVx8RkjnZncArFPbDs6xgH9d/FiNK4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}