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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ac0b64024b087a996d65eb4726449826414530a696253a2f8c85bd7d10637a' 
  AND token = 'jeCw+mJ1LToE9DdnyjtDsYZMv+iNW4QcUJv+/3376rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}