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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765cfa69d2c2e49689f935e25c951e9430ea12f3a5d141769b62468c0d18e429' 
  AND token = 'H3lctlCiU21ECbXcYfR+TPGLeQvlNWh8Brkg+T6d1pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}