SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01bdb144d52c0662c519cb832d3faf643d7c487086eccd028cb778827d99f477' 
  AND token = 'dv+DHt/Qp0PcTqicHGo8/YDQbOXwo0T65/eRpcs0BMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}