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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db75cf4894e68c6cea7d7fc9197bcec01517b7ad7aa900f1593eb8985c89d512' 
  AND token = 'kZVBLYRv+sfstl7yPSFV3JmA3y6z4O5X10JOIlFUm3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}