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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9541e92b80403e827592a181e8d7d5cb18f243374f29e6bb6b452431f3439e3' 
  AND token = '3UUhHhtaVosunA/5pNLg3lAPvkQbPqmb0r4/0XsZBY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}