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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efdd8d4aa66bd97a158f49da2e3dc852206248ef1a6117d67b072d80af3cd6c6' 
  AND token = 'MeJ2FJqhMysJdeaAZGcXF/0PpXgtDawjShIDFxoTOs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}