SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8899158f5cad71c1ec1fe4b292e6ac2736f8232d476be402caf9d55a56a1063d' 
  AND token = 'pUFx09mGNZ6rqPJSgsDztZwbFIn1eRuZNofxzMb8eH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}