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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da01337c25f8eda6f405ab17b40463bd774d074356a1471827a45df3ce1bb5e0' 
  AND token = 'wSnKyfTWfa7ZKRNNkJHlRfsPC5K1gAtDhw9R6KCTavc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}