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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260d5e72235e444c93159f5ce27dab6408376bd1d89db803ab7f4bd72eb59bda' 
  AND token = 'v49TJHMw4NKPYIgyWwKutMHkFcNN89Z1Z5Jm2NRG6HU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}