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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e065aa66b22ce16f9996de6b419f6d248b6ea300d5e7c37a6f1ba5a01e6a561d' 
  AND token = '34+eGL0+D3iM8ShT7xM59VI7aSLxvq7bjOOjXx/Xlig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}