SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0ac7b7d6f06d4321a593ecd459b55c41d885d2b9c23b26d690dcf66bbf25b7' 
  AND token = '3HLOsuauyVlxupbmT6tGrJRW3kGzJlrvrF8gimnInSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}