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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc6e454e2fddedd8e1103d5e4e81c2a8f89e07f351ff3965e8a1b0001f71433' 
  AND token = 'p9n5LU20DXzCfSkZ94sT+CbGlgpwgGYFqZ05nmS0nOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}