SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0218dfe059a418e73952b026d9b4cb6cf29210260ba87ec1f323876a31846e' 
  AND token = '6D5rWoAjJJjZQvE1S+xHTob4hFRweEKmTpJwgeI3EhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}