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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b6f60a1297da7b8143bd299ca4620bfff4e2690e0f423dc1f17744e1eec94e' 
  AND token = 'BUyQdf7kSKSvlwRf9g2nTlsaIn2oePLhyTGwiqQ/nh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}