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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09cc72a3574036be0ee8d45b018246869e94c7783f4de9dae9bbb203c41c356' 
  AND token = 'l8NLpM1Ov//Mnr632TZussvyrzF9td0drmBO5+yWkOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}