SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2fd6d0a652cfad6581575eff1a83e020196a790982dfe43224dda325aa18b1e' 
  AND token = '3cb+tVhnM5gIviuNw1oK+ym2RW2GpBDojj5VWb5ZXr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}