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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1dbc0249269a644c38797987291d0a8a8787cec20b799718def4954d72c4263' 
  AND token = 'op3uZTuLwg0dSF0ZDUGcuAu4PI/t/Fx5alGeoGYqZ+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}