SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dead2e81b46d0bc0d631efdb4e5ab67e4aa6419211ef5e8a8e52477d50a95cce' 
  AND token = 'V+MmEKV/toiwURFkFssdlHgqd4NSOt/5TFpIlEPyZCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}