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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '674c4e7c623cd809384fda6a65357bddbfb6bb2de03c81dcf43962c46afe4437' 
  AND token = 'vG5yRKXTu1J4mkW0BoCOw+n4TRVsHln4PbgM2Q60LLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}