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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ca238b2c132c0b35679ee93a214daf8de9d57770b65f33e6ca3a83849df556' 
  AND token = 'UZIwzkUgFRiTlq9MGS1Xmb99NSYci8pxtmUiAjaclIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}