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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65eee5f7c9e58b40baf40b93d8e9f50a8afc7d5072df36f895bc48343b42c52' 
  AND token = 'XaDNM2npHSdAdL4N3yz1u7Rcwux2fmzwwyNtThY5jB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}