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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837470da76aae7a1e7369f3d112e03bd48c9ff1284df17fa2a8e0a352d6c38cc' 
  AND token = 'zQm/CNJTtic51Mjs8oYJbyM0XBphGpcI9xdnp2e1FGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}