SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb7e0a8e72e62d29711c9cdf887961e3c6838968bcea01e4b0d9fdbc875407c' 
  AND token = 'rUMYUVT1qp8MXVTqsR0oAhuCempJD9I0nS7sJ92J+kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}