SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f99ed56e5d945dda7de02692dbd4e3fdf53b89ce7c9d1b79984d579c57fd403' 
  AND token = 'YbX0hDSvddovsyS2XFivxohGtE3NxXZFeyiydLiTHXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}