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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4daf29d259c8d6430da09c3f6c53e4f39309824367e478d2b1cd04493d519c' 
  AND token = 'YEgOWlw30jgPw7ujUmy/duLP+enqK+mESnD/SJfSER8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}