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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b02101101ff591c597ede929ab0c35c614d9aecfefef7212c79e75fbf43eec5' 
  AND token = '9Vu9bMdGLoViIYdV2nXlS9DmRmYUUEMpf7kMUI8QqyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}