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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e5eb8156b2102e3ba9331f86144f90f548e8a58bcef58e67cc19881ae6129d' 
  AND token = 'orGrTt/mvl+apO2iblYa/HzW02kNWijWUZ324it9Lww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}