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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f4fc40385c9836b96345305da61ac9cf6cdc5b216e7d76e4908ae1cd436b863' 
  AND token = 'G+ipFMbc7P1M0u8XOrV+i5QCx3uFaoCnBHKSK52rP9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}