SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f5016c99d858140adaa64d5f99fb00398c974b9e8d359f5a19bf05fa27821d' 
  AND token = '5o6hr40siWyMOBk5UnkGF8tZ31xHHAJx6OZEOkd23JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}