SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a14c21d75212c2ce1718cf2eb4c00a7f6f575d16079bddf870c5ad8800f772b' 
  AND token = '+O2uL/P3WJXKifBAMbZQSBKOKWNd/fRjjOeMY4oBM9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}