SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111d3aafe5ee601ab64035852256fb2c73212e00130d089b31d96fd88b79e9b8' 
  AND token = 'jV+Rqx+ubn5k38whEvxqzW7g/tO/0dcKUd8k87PTf9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}