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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b321b31f6fe807a7571dc2db8bd0b86cbc8883454609f62e19ecc55b20aa854b' 
  AND token = 'TElqag4q0FXZNJ+KX670pWUkp/7in2s3COG1WikZjfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}